Development of pH-responsive polymer-grafted mesoporous silica
نویسندگان
چکیده
منابع مشابه
Light-responsive nanogated ensemble based on polymer grafted mesoporous silica hybrid nanoparticles.
Mesoporous silica nanoparticles grafted with light-responsive polymer on the outer surface were developed as novel nanogated ensembles, which allow encapsulation and release of drug and biological molecules under light irradiation.
متن کاملMultifunctional polymer-capped mesoporous silica nanoparticles for pH-responsive targeted drug delivery.
A highly stable modular platform, based on the sequential covalent attachment of different functionalities to the surface of core-shell mesoporous silica nanoparticles (MSNs) for targeted drug delivery is presented. A reversible pH-responsive cap system based on covalently attached poly(2-vinylpyridine) (PVP) was developed as drug release mechanism. Our platform offers (i) tuneable interactions...
متن کاملSupporting Information Multifunctional Polymer-Capped Mesoporous Silica Nanoparticles for pH-Responsive Targeted Drug Delivery
1Department of Chemistry, Nanosystems Initiative Munich (NIM) and Center for Nano Science (CeNS), University of Munich (LMU), Butenandtstr. 11 (E), 81377 Munich, Germany 2Department of Pharmacy, Pharmaceutical Biotechnology, Nanosystems Initiative Munich (NIM) and Center for Nano Science (CeNS), University of Munich (LMU), Butenandtstr. 5-13, 81377 Munich, Germany # authors contributed equally ...
متن کاملpH-Responsive Mesoporous Silica and Carbon Nanoparticles for Drug Delivery
The application of nanotechnology to medicine constitutes a major field of research nowadays. In particular, the use of mesoporous silica and carbon nanoparticles has attracted the attention of numerous researchers due to their unique properties, especially when applied to cancer treatment. Many strategies based on stimuli-responsive nanocarriers have been developed to control the drug release ...
متن کاملSurface Immobilization of pH-Responsive Polymer Brushes on Mesoporous Silica Nanoparticles by Enzyme Mimetic Catalytic ATRP for Controlled Cargo Release
Peroxidase mimetic catalytic atom transfer radical polymerization (ATRP) was first used to install tertiary amine-functionalized polymer brushes on the surface of mesoporous silica nanoparticles (MSNs) in a facile and highly efficient manner. Poly(N,N-dimethylaminoethyl methacrylate) (PDMAEMA) brushes-grafted MSNs were fabricated by biocompatible deuteroheminβ-Ala-His-Thr-Val-Glu-Lys (DhHP-6)-c...
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ژورنال
عنوان ژورنال: Transactions of the Materials Research Society of Japan
سال: 2013
ISSN: 1382-3469,2188-1650
DOI: 10.14723/tmrsj.38.597